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Gender differences in the rat corpus callosum: An ultrastructure study
Author(s) -
Al Qattan Duaa,
Shatarat Amjad,
Alzghoul Loai,
Khaled Aya,
Abdallah Ala,
ELBeltagy Maha
Publication year - 2019
Publication title -
anatomia, histologia, embryologia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.34
H-Index - 35
eISSN - 1439-0264
pISSN - 0340-2096
DOI - 10.1111/ahe.12464
Subject(s) - corpus callosum , sexual dimorphism , splenium , anatomy , biology , ultrastructure , adult male , central nervous system , neuroscience , medicine , zoology , white matter , endocrinology , magnetic resonance imaging , radiology
Sexual dimorphism exists at all levels of the nervous system, from genetic, anatomical and system levels. The sexual dimorphism in the axonal content of the corpus callosum (CC) has always been controversial; hence, the aim of this study was to analyse the differences in total, myelinated and unmyelinated axons density of various regions of the CC between male and female rats. To assess that, six pairs of adult male and female rats were perfused and the CC was removed and sectioned. Four sections from different subregions of the corpus callosum that represent the genu, anterior body, posterior body, and splenium, were stained, and electron microscopic images were captured using stereological guidelines. Later, the axons density for each subregion was calculated and compared between males and females. The findings of the present study indicated region‐specific differences in the myelinated, unmyelinated or the ratio of myelinated/total axons in the CC between male and female rats.