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Orexin‐B‐like immunoreactivity in pituitary αMSH‐producing cells and median eminence GnRH‐containing fibres of the flat‐tailed house gecko
Author(s) -
Suzuki Hirohumi,
Yamamoto Toshiharu
Publication year - 2019
Publication title -
anatomia, histologia, embryologia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.34
H-Index - 35
eISSN - 1439-0264
pISSN - 0340-2096
DOI - 10.1111/ahe.12461
Subject(s) - median eminence , gecko , anatomy , biology , medicine , endocrinology , hypothalamus , zoology
We examined the distribution of the orexin‐like peptides in the pituitary and median eminence of the flat‐tailed house gecko ( Hemidactylus platyurus ) using immunohistochemistry. Orexin‐B‐like, but not orexin‐A‐like, immunoreactivity was detected in the pituitary, specifically in the pars intermedia, and these cells corresponded to alpha‐melanocyte‐stimulating hormone (αMSH)‐producing cells. Orexin‐B and αMSH secreted from pars intermedia may modulate secretion of adenohypophyseal cells in the pars distalis. In the median eminence, orexin‐B‐immunoreactive puncta and fibres were observed, and these structures corresponded to gonadotropin‐releasing hormone (GnRH)‐immunoreactive puncta and fibres. Orexin‐B secreted from GnRH‐containing neurons in the hypothalamus may affect thyrotropin‐releasing hormone‐containing neurons resulting in modulation of αMSH secretion of melanotrophs in the pars intermedia.