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Ultrastructure of plasma cells in harderian gland of laying hens
Author(s) -
Bejdić P.,
Avdić R.,
Amidžić Lj.,
Ćutahija V.,
Tandir F.,
Hadžiomerović N.,
Katica A.,
Mlaćo N.
Publication year - 2018
Publication title -
anatomia, histologia, embryologia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.34
H-Index - 35
eISSN - 1439-0264
pISSN - 0340-2096
DOI - 10.1111/ahe.12322
Subject(s) - ultrastructure , harderian gland , endoplasmic reticulum , biology , stroma , plasma cell , microbiology and biotechnology , cell type , epithelium , antibody , endocrinology , pathology , anatomy , cell , immunohistochemistry , immunology , medicine , biochemistry , genetics
Summary Ultrastructure of plasma cells in Harderian gland was investigated using the transmission electron microscopy. For this research, we examined the glands of 32 laying hens collected at 1, 7, 20 and 40 days and 4, 6, 8 and 12 months of the birds' ages. The research showed that the stroma of the gland contains a large number of lymphocytes and plasma cells. Most of the plasma cells are mature, but morphologically do not show productive activity. Only some individual plasma cells, situated under the secretory epithelium of primary and secondary ducts, have extremely dilated cisternae of rough endoplasmic reticulum which contain moderately dense, granular material. The morphology of these cells indicates that they are in active stage of immunoglobulin production. Also, we identified plasma cells with two types of Russell bodies. One type of these bodies was small, round or oval, while the other had irregular, angular shape. It was noted that one plasma cell never contains both type of Russell bodies at the same time. These cells were often affected by apoptosis. Among them, in deeper part of the stroma, were situated the small plasmablast cells.