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A joint analysis strategy reveals genetic changes associated with artificial selection between egg‐type and meat‐type ducks
Author(s) -
Gu H.,
Zhu T.,
Li X.,
Chen Y.,
Wang L.,
Lv X.,
Yang W.,
Jia Y.,
Jiang Z.,
Qu L.
Publication year - 2020
Publication title -
animal genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.756
H-Index - 81
eISSN - 1365-2052
pISSN - 0268-9146
DOI - 10.1111/age.13014
Subject(s) - biology , transcriptome , gene , genetics , genome , phenotype , candidate gene , rna seq , selection (genetic algorithm) , natural selection , evolutionary biology , computational biology , gene expression , artificial intelligence , computer science
Summary Egg‐type ducks and meat‐type ducks are predominantly commercial or indigenous and have been subjected to artificial directional selection. These two duck types differ substantially in body shape, production performance and reproductivity. However, the genetic changes associated with phenotypic differences remain unclear. Here, we compared the two duck types at the genomic and transcriptomic levels. We identified a large number of SNPs and genes in genomic divergent regions in terms of F ST and θπ values. The corresponding genes were mainly enriched in embryonic development function and metabolic pathway. RNA‐seq analysis also revealed differential gene expression in the liver and gonads. The differentially expressed genes were functionally associated with signal transmission and substance metabolism respectively. Furthermore, we found that seven genes were related to differentiation between the two types by both g genome and transcriptome analysis and were plausible candidate genes. These genes were annotated to GO categories of cell development and disease immunity. These findings will enable a better understanding of the artificial selection history of meat and egg ducks and provide a valuable resource for future research on the breeding of these two lineages.