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Genome‐wide association study identifies loci linked to serum electrolyte traits in Chinese Holstein cattle
Author(s) -
Gan Q. F.,
Li Y. R.,
Lund M.,
Su G. S.,
Liang X. W.
Publication year - 2019
Publication title -
animal genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.756
H-Index - 81
eISSN - 1365-2052
pISSN - 0268-9146
DOI - 10.1111/age.12851
Subject(s) - biology , genome wide association study , quantitative trait locus , single nucleotide polymorphism , genetics , calcium , gene , chromosome , potassium , genetic association , sodium , genotype , medicine , chemistry , organic chemistry
Summary We aimed to identify QTL for serum electrolyte traits by performing a GWAS of calcium, chloride, sodium, potassium and magnesium ion concentrations in Chinese Holstein cattle. We detected five SNPs that had significant associations with calcium ion concentrations and identified GATA 2 from Bos taurus chromosome ( BTA )22 as having the highest significance. Among the genes with significant results, we speculate that TMEM 123 might be related to calcium channel proteins according to the functions of the TMEM family.