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Genome‐wide association study reveals candidate genes associated with body measurement traits in Chinese Wagyu beef cattle
Author(s) -
An B.,
Xia J.,
Chang T.,
Wang X.,
Xu L.,
Zhang L.,
Gao X.,
Chen Y.,
Li J.,
Gao H.
Publication year - 2019
Publication title -
animal genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.756
H-Index - 81
eISSN - 1365-2052
pISSN - 0268-9146
DOI - 10.1111/age.12805
Subject(s) - biology , candidate gene , genetics , snp , beef cattle , genome wide association study , gene , genome , genetic association , single nucleotide polymorphism , genotype
Summary We performed a genome‐wide association study to identify candidate genes for body measurement traits in 463 Wagyu beef cattle typed with the Illumina Bovine HD 770K SNP array. At the genome‐wide level, we detected 18, five and one SNP s associated with hip height, body height and body length respectively. In total, these SNP s are within or near 11 genes, six of which ( PENK , XKR 4, IMPAD 1 , PLAG 1 , CCND 2 and SNTG 1 ) have been reported previously and five of which ( CSMD 3 , LAP 3 , SYN 3 , FAM 19A5 and TIMP 3 ) are novel candidate genes that we found to be associated with body measurement traits. Further exploration of these candidate genes will facilitate genetic improvement in Chinese Wagyu beef cattle.