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Lnc RNA net: a comprehensive Sus scrofa lnc RNA database
Author(s) -
Liang G.,
Yang Y.,
Li H.,
Yu H.,
Li X.,
Tang Z.,
Li K.
Publication year - 2018
Publication title -
animal genetics
Language(s) - Spanish
Resource type - Journals
SCImago Journal Rank - 0.756
H-Index - 81
eISSN - 1365-2052
pISSN - 0268-9146
DOI - 10.1111/age.12720
Subject(s) - biology , long non coding rna , computational biology , database , genetics , gene , rna , computer science
Long noncoding RNAs (lncRNAs) constitute a large class of functional non-coding RNAs that play important roles in many biological processes. Thousands of lncRNAs have been identified in mammals. Pig is an important farm animal and biomedical model. It is essential to create a Sus scrofa lncRNA database to enable further study of the function and evolution of lncRNAs. In this study, we built a systematic S. scrofa lncRNA database named lncRNAnet that contains 53 468 S. scrofa lncRNAs with their sequence characteristics, genomic locations, conservation, overlapping SNPs and QTLs, and transcript abundance across nine tissues in pigs. We also integrated 212 922 human and mouse lncRNAs sequences into lncRNAnet. This database will provide for a systematic S. scrofa lncRNA classification and help investigators browse, search for and analyze lncRNAs as well as do blast searches among human, mouse and pig lncRNAs. Thus, lncRNAnet should improve the understanding of the biological functions of lncRNA. The database is freely accessible at http://lnc.rnanet.org/.