Genome‐scale identification of mi RNA – mRNA and mi RNA –lnc RNA interactions in domestic animals

Summary Domestic animals show considerable genetic diversity. Previous studies suggested that animal phenotypes were affected by mi RNA – mRNA interplay, but these studies focused mainly on the analysis of one or several mi RNA – mRNA interactions. However, in this study, we investigated mi RNA – mRNA and mi RNA –lnc RNA interactions on a genomic scale using miranda and targetscan algorithms. There has been strong directional artificial selection practiced during the domestication of animals. Thus, we investigated SNP s that were located in mi RNA s and mi RNA binding sites and found that several SNP s located in 3′‐ UTR s of mRNA s had the potential to affect mi RNA – mRNA interactions. In addition, a database, named mi RB ond, was developed to provide visualization, analysis and downloading of the resulting datasets. Our results open the way to further experimental verification of mi RNA – mRNA and mi RNA –lnc RNA interactions as well as the influence of SNP s upon such interplay.