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Clinical and microbiological characterization of localized aggressive periodontitis: a cohort study
Author(s) -
OettingerBarak O,
Sela MN,
Sprecher H,
Machtei EE
Publication year - 2014
Publication title -
australian dental journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.701
H-Index - 71
eISSN - 1834-7819
pISSN - 0045-0421
DOI - 10.1111/adj.12165
Subject(s) - tannerella forsythia , fusobacterium nucleatum , aggregatibacter actinomycetemcomitans , prevotella intermedia , medicine , aggressive periodontitis , periodontitis , chronic periodontitis , population , microbiology and biotechnology , porphyromonas gingivalis , biology , pathology , honeysuckle , alternative medicine , environmental health , traditional chinese medicine
Background Localized aggressive periodontitis ( LA gP) is an infectious periodontal disease which generally affects young people. Recent data suggest the involvement of different bacterial species in different populations. The causative bacterial species in Israel has never been identified despite a high prevalence of LA gP in this population. The objectives of this study were to characterize the bacterial microbiota of periodontal pockets within an Israeli LA gP population who were also clinically assessed. Methods Twenty‐one LA gP patients (test) and 12 chronic periodontitis patients (control) were examined. Bacterial samples were collected from periodontal pockets and analysed by both culture and polymerase chain reaction techniques. Mann–Whitney U test and chi‐square test were used to compare results between the groups. Results Higher levels of Parvimonas micra (>10 6 ), Aggregatibacter actinomycetemcomitans (>10 5 ), Fusobacterium nucleatum/F. periodonticum (>10 6 ), and Tannerella forsythia (levels of 10 5 to 10 6 bacteria) were detected in the LA gP group compared to the control (p < 0.05), while levels of Porphyromonas gingivalis and Prevotella intermedia were higher in the CP group. Conclusions The characteristic periodontal bacterial flora of LA gP patients in Israel is mainly comprised of P. micra, A. actinomycetemcomitans, F. nucleatum/F. periodonticum and T. forsythia . Similar population based studies of each population will improve the quality of treatment of LA gP when individual sampling is not possible.