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How can we investigate the role of topiramate in the treatment of cocaine use disorder more thoroughly?
Author(s) -
Klimas Jan,
Wood Evan,
Werb Daniel
Publication year - 2017
Publication title -
addiction
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.424
H-Index - 193
eISSN - 1360-0443
pISSN - 0965-2140
DOI - 10.1111/add.13618
Subject(s) - craving , topiramate , psychology , psychiatry , cocaine dependence , clinical psychology , population , placebo , impulsivity , contingency management , clinical trial , cocaine use , addiction , medicine , intervention (counseling) , alternative medicine , environmental health , pathology , epilepsy
We read with interest Drs Darke and Farrell’s commentary on our meta-analysis of Topiramate published in the eight issue of 2016. To elaborate on some of the ideas raised by the commentary, we focus our response on the question of why some studies implied a benefit and others did not. Overall, although the current evidence is not strong enough to support the routine clinical use of Topiramate for the treatment of cocaine use disorder, it may be useful for researching in certain circumstances in terms of helping people with cocaine use disorders stay abstinent from cocaine use