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Binge Drinking–Induced Subtle Myocardial Injury
Author(s) -
Waszkiewicz Napoleon,
Szulc Agata,
Zwierz Krzysztof
Publication year - 2013
Publication title -
alcoholism: clinical and experimental research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.267
H-Index - 153
eISSN - 1530-0277
pISSN - 0145-6008
DOI - 10.1111/acer.12208
Subject(s) - medicine , cardiology , myocardial infarction , binge drinking , cardiotoxicity , alcohol and health , blood pressure , alcohol , poison control , injury prevention , alcohol consumption , medical emergency , toxicity , biochemistry , chemistry
Background Most of the clinical, histopathological, and biochemical studies consider the effect of chronic alcohol intoxication on myocardial injury. Much less attention has been paid to acute alcohol (binge drinking)–induced cardiotoxicity, even though alcohol binging is much more common than alcohol dependence. Methods We briefly present some of the binge drinking–induced “holiday heart” effects. The literature was searched to find effects of alcohol on heart. Results In binge drinking, the literature has demonstrated transient myocardial subtle changes in cardiac magnetic resonance, increased serological markers of myocardial injury and inflammation, abnormal cardiac rhythm, changes in other biochemical and ultrastructural indices of myocardial dysfunction, as well as changes in metabolism, blood pressure, heart rate, thrombosis/fibrinolysis processes, and coronary vasoconstriction. Conclusions Although acute low alcohol exposure has widely proven positive effect on myocardial function, heavy acute drinking frequent events are related to adverse cardiovascular effects.