Open AccessThyroid hormones in diabetes, cancer, and aging
Author(s) -
Gauthier Benoit R.,
SolaGarcía Alejandro,
CálizMolina María Ángeles,
Lorenzo Petra Isabel,
CoboVuilleumier Nadia,
CapillaGonzález Vivian,
MartinMontalvo Alejandro
Publication year - 2020
Publication title -
aging cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.103
H-Index - 140
eISSN - 1474-9726
pISSN - 1474-9718
DOI - 10.1111/acel.13260
Subject(s) - hormone , thyroid , diabetes mellitus , longevity , thyroid function , biology , type 2 diabetes , cancer , endocrinology , medicine , bioinformatics , physiology , gerontology
Thyroid hormones are central in the control of health and disease. Here we review the latest findings in thyroid hormone research in the field of diabetes, cancer, and aging. Aging studies indicate that the direct modulation of thyroid hormones is not an viable strategy to promote healthy aging. However, although challenging, interventions based on the use of modulators of thyroid hormone function might provide therapeutic benefit in certain types of diabetes and cancers.