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Use of prokinetic agents in hospitalised adult patients: Protocol for a scoping review
Author(s) -
Crone Vera,
Møller Morten Hylander,
Perner Anders,
Alhazzani Waleed,
Krag Mette
Publication year - 2022
Publication title -
acta anaesthesiologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.738
H-Index - 107
eISSN - 1399-6576
pISSN - 0001-5172
DOI - 10.1111/aas.14099
Subject(s) - medicine , prokinetic agent , intensive care medicine , grading (engineering) , protocol (science) , medline , systematic review , alternative medicine , pharmacology , pathology , civil engineering , political science , law , engineering
Background Gastrointestinal motility is an important contributor to the effective uptake of water and nutrition. However, it is often impaired in acutely ill hospitalised patients. Amongst other indications, prokinetic agents are used to improve GI motility, but the body of evidence is not well described. Accordingly, we aim to systematically describe and explore the body of evidence on the use of prokinetic agents in hospitalised adults. Methods In accordance with the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses extension for Scoping Reviews statement, we plan to conduct a scoping review of studies assessing the use of prokinetic agents, for any indication, in hospitalised adults. We plan to assess study design, population, agents, indications and outcomes across included studies. When applicable, we plan to assess the certainty of evidence using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach. Results We plan to provide descriptive analyses of the included studies accompanied by tabulated results and characterise knowledge gaps. Conclusion The outlined scoping review will provide a summary of the body of evidence on the use, indications, effects and side effects of prokinetic agents in hospitalised adults.