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Meta‐analyses of gabapentinoids for pain management after knee arthroplasty: A caveat emptor? A narrative review
Author(s) -
Joshi Girish P.,
Kehlet Henrik
Publication year - 2021
Publication title -
acta anaesthesiologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.738
H-Index - 107
eISSN - 1399-6576
pISSN - 0001-5172
DOI - 10.1111/aas.13820
Subject(s) - medicine , caveat emptor , meta analysis , perioperative , narrative review , arthroplasty , physical therapy , pain management , total knee arthroplasty , medline , general surgery , surgery , intensive care medicine , management , political science , law , economics
The use of gabapentinoids for perioperative pain management after total knee arthroplasty has been the subject of nine systematic reviews and meta‐analyses. A critical analysis of the clinical aspects of the methodology of these publications shows major flaws which limit the interpretation for the recommended use of perioperative gabapentinoids in pain management for unilateral primary total knee arthroplasty. Consequently, readers and authors of systematic reviews and meta‐analyses should critically assess the clinical aspects of the included studies.