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Predictive variables for poor long‐term physical recovery after intensive care unit stay: An exploratory study
Author(s) -
Ámundadóttir Ólöf R.,
Jónasdóttir Rannveig J.,
Sigvaldason Kristinn,
Jónsdóttir Helga,
Möller Alma D.,
Dean Elizabeth,
Sveinsson Thorarinn,
Sigurðsson Gísli H.
Publication year - 2020
Publication title -
acta anaesthesiologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.738
H-Index - 107
eISSN - 1399-6576
pISSN - 0001-5172
DOI - 10.1111/aas.13690
Subject(s) - medicine , term (time) , intensive care unit , intensive care medicine , emergency medicine , quantum mechanics , physics
Background Elucidating factors that influence physical recovery of survivors after an intensive care unit (ICU) stay is paramount in maximizing long‐term functional outcomes. We examined potential predictors for poor long‐term physical recovery in ICU survivors. Methods Based on secondary analysis of a trial of 50 ICU patients who underwent mobilization in the ICU and were followed for one year, linear regression analysis examined the associations of exposure variables (baseline characteristics, severity of illness variables, ICU‐related variables, and lengths of ICU and hospital stay), with physical recovery variables (muscle strength, exercise capacity, and self‐reported physical function), measured one year after ICU discharge. Results When the data were adjusted for age, female gender was associated with reduced muscle strength ( P = .003), exercise capacity ( P < .0001), and self‐reported physical function ( P = .01). Older age, when adjusted for gender, was associated with reduced exercise capacity ( P < .001). After adjusting for gender and age, an association was observed between a lower score on one or two physical recovery variables and exposure variables, specifically, high body mass index, low functional independence, comorbidity and low self‐reported physical function at baseline, muscle weakness at ICU discharge, and longer hospital stay. No adjustment was made for cumulative type I error rate due to small number of participants. Conclusion Elucidating risk factors for poor long‐term physical recovery after ICU stay, including gender, may be critical if mobilization and exercise are to be prescribed expediently during and after ICU stay, to ensure maximal long‐term recovery.