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Effects of anaesthesia‐induced hypotension and phenylephrine on plasma volume expansion by hydroxyethyl starch: A randomised controlled study
Author(s) -
Kaneko Takahiko,
Tatara Tsuneo,
Hirose Munetaka
Publication year - 2020
Publication title -
acta anaesthesiologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.738
H-Index - 107
eISSN - 1399-6576
pISSN - 0001-5172
DOI - 10.1111/aas.13548
Subject(s) - medicine , hydroxyethyl starch , anesthesia , phenylephrine , hetastarch , blood volume , blood pressure , saline , general anaesthesia , abdominal surgery
Changes in blood haemoglobin concentration indicate plasma volume expansion following hydroxyethyl starch (HES) infusion, but may be affected by vascular tone and HES-induced shedding of the endothelial surface layer (ESL). We hypothesised that anaesthesia-induced hypotension enhances changes in plasma volume as assessed by blood haemoglobin concentration (ΔPV Hb , %) following HES infusion.