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Capnocytophaga canimorsus bacteremia: clinical features and outcomes from a Helsinki ICU cohort
Author(s) -
Hästbacka J.,
Hynninen M.,
Kolho E.
Publication year - 2016
Publication title -
acta anaesthesiologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.738
H-Index - 107
eISSN - 1399-6576
pISSN - 0001-5172
DOI - 10.1111/aas.12752
Subject(s) - medicine , bacteremia , septic shock , capnocytophaga , sepsis , coagulopathy , intensive care unit , intensive care medicine , acute kidney injury , surgery , microbiology and biotechnology , genetics , antibiotics , bacteria , biology
Background Capnocytophaga canimorsus is a gram‐negative rod capable of causing severe sepsis or septic shock. We studied the characteristics of patients with C. canimorsus bacteremia treated in intensive care unit ( ICU ). Methods Patients with C. canimorsus bacteremia in the Helsinki University Hospital district from 2005 to 2014 were retrospectively reviewed using laboratory database and electronical patient records. Results We identified 65 patients with C.canimorsus bacteremia. Of these, 16 (25%) were treated in an ICU . The most commonly affected organ systems were coagulation (94%) and kidney (69%). Mortality of ICU treated patients was 19%. Three survivors underwent lower limb amputations for gangrene. Only 25% of the patients were immune‐compromised, but alcohol abuse was common (69%). All patients had a contact with dogs, but only 37% had a history of a dog‐bite. Conclusion Capnocytophaga canimorsus infection may present with severe sepsis or septic shock with organ dysfunction, most frequently coagulopathy and acute kidney injury. Previously recognized risk factors are not always present. A dog in a household may be a sufficient exposure for developing a severe form of the disease. The possibility of C. canimorsus infection should be considered in patients with any contact with dogs, even in immunocompetent patients.