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Optimising abdominal space with deep neuromuscular blockade in gynaecologic laparoscopy – a randomised, blinded crossover study
Author(s) -
MADSEN M. V.,
GÄTKE M. R.,
SPRINGBORG H. H.,
ROSENBERG J.,
LUND J.,
ISTRE O.
Publication year - 2015
Publication title -
acta anaesthesiologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.738
H-Index - 107
eISSN - 1399-6576
pISSN - 0001-5172
DOI - 10.1111/aas.12493
Subject(s) - medicine , pneumoperitoneum , insufflation , laparoscopy , anesthesia , abdomen , surgery , fascia , anterior compartment of thigh , thigh
Background Insufflation of the abdomen during laparoscopy improves surgical space, but may cause post‐operative shoulder pain. The incidence of shoulder pain is reduced using a lower insufflation pressure, but this may, however, compromise the surgical space. We aimed at investigating whether deep neuromuscular blockade ( NMB ) would enlarge surgical space, measured as the distance from the sacral promontory to the trocar in patients undergoing gynaecologic laparoscopy. Methods Fourteen patients were randomised in an assessor‐blinded crossover design. The distance from the sacral promontory to the trocar was measured during deep NMB and without NMB at pneumoperitoneum 8 and 12 mmHg both. Additionally, we assessed surgical conditions while suturing the abdominal fascia using a 4‐point subjective rating scale. Deep NMB was established with rocuronium and reversed with sugammadex. Results At 12 mmHg pneumoperitoneum, deep NMB improved surgical space with a mean of 0.33 cm (95% confidence interval 0.07–0.59) ( P = 0.01, paired t ‐test) compared with no NMB . At 8 mmHg pneumoperitoneum deep NMB improved surgical space with a mean of 0.3 cm (95% confidence interval, 0.06–0.54) ( P = 0.005) compared with no NMB . Deep NMB resulted in significantly better ratings of surgical conditions during suturing of the fascia ( P = 0.03, M ann– W hitney U ‐test). Conclusion Deep NMB enlarged surgical space measured as the distance from the sacral promontory to the trocar. The enlargement, however, was minor and the clinical significance is unknown. Moreover, deep NMB improved surgical conditions when suturing the abdominal fascia.