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Association of mortality with out‐of‐hours admission in patients with perforated peptic ulcer
Author(s) -
KNUDSEN N. V.,
MØLLER M. H.
Publication year - 2015
Publication title -
acta anaesthesiologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.738
H-Index - 107
eISSN - 1399-6576
pISSN - 0001-5172
DOI - 10.1111/aas.12450
Subject(s) - medicine , odds ratio , confidence interval , peptic ulcer , mortality rate , gastroenterology , cohort , surgery
Background Perforated peptic ulcer is a serious emergency surgical condition. The aim of the present nationwide cohort study was to evaluate the association between mortality and out‐of‐hours admission in patients surgically treated for perforated peptic ulcer. Methods All D anish patients surgically treated for benign gastric or duodenal perforated peptic ulcer in D enmark between S eptember 1, 2011 and A ugust 31, 2013 were included. Patients were identified through T he D anish C linical R egister of E mergency S urgery. The association between 90‐day mortality and time and day of admission and surgery was assessed by crude and adjusted odds ratios ( OR s) with 95% confidence intervals ( CI s). Results A total of 726 patients were included. Median age was 69.5 years (range 18.2–101.7), and 569 of the 726 patients (78.4%) had at least one coexisting disease. Adjusted OR s and 95% CI s between 90‐day mortality and admission in daytime vs. nighttime and weekday vs. weekend were 1.0 (0.7–1.5) and 1.2 (0.8–1.8), respectively. Adjusted OR s with 95% CI between surgery in daytime vs. nighttime and weekday vs. weekend were 0.9 (0.6–1.3) and 1.2 (0.8–1.8), respectively. Sensitivity analysis was consistent with the primary analysis. The overall 90‐day mortality rate was 25.6% (186/726). Conclusion No statistically significant adjusted association between 90‐day mortality and out‐of‐hours admission was found in patients surgically treated for perforated peptic ulcer.