Open AccessPerivascular epithelioid cell tumor of the lung: A case report and literature review
Author(s) -
Yu Shaofu,
Zhai Shasha,
Gong Qian,
Hu Xiaoping,
Yang Wenjuan,
Liu Liyu,
Kong Yi,
Wu Lin,
Pu Xingxiang
Publication year - 2022
Publication title -
thoracic cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.823
H-Index - 28
eISSN - 1759-7714
pISSN - 1759-7706
DOI - 10.1111/1759-7714.14583
Subject(s) - medicine , perivascular epithelioid cell , pathology , lung , epithelioid cell , lung cancer , biopsy , pneumonectomy , thoracotomy , anatomy , immunohistochemistry
The perivascular epithelioid cell tumor (PEComa) is a rare tumor of interstitial origin characterized by several immunological and muscle cell markers. The clear cell sugar tumor (CCST) of the lung is a type of PEComa defined by thin cell walls and high levels of glycogen in the cytoplasm. We herein reported the case of a 48‐year‐old male with a recurrence of lung CCST. The preoperative diagnosis of the lung mass was performed by percutaneous needle biopsy. During the thoracoscopic resection, multiple adhesions in the thoracic cavity were described. The tumor invaded the chest wall, and the boundaries between the tumor and surrounding normal tissues were unclear. The mediastinal lymph nodes were significantly enlarged. No relevant gene mutations were detected. After concomitant chemoradiotherapy, the patient's condition was stable. We also conducted a literature review and discussed the overall findings.