Open AccessDiagnostic utility of transbronchial biopsy for Hodgkin's lymphoma: A case study
Author(s) -
Hoshi Miki,
Kobayashi Nobuaki,
Tanaka Katsushi,
Somekawa Kohei,
Kaneko Ayami,
Izawa Ami,
Seki Kenichi,
Tagami Yoichi,
Aoki Ayako,
Fujii Hiroaki,
Watanabe Keisuke,
Horita Nobuyuki,
Hara Yu,
Matsumura Mai,
Enaka Makiko,
Hagihara Maki,
Kaneko Takeshi
Publication year - 2021
Publication title -
thoracic cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.823
H-Index - 28
eISSN - 1759-7714
pISSN - 1759-7706
DOI - 10.1111/1759-7714.14190
Subject(s) - medicine , dacarbazine , vinblastine , biopsy , lymphoma , radiology , lung , brentuximab vedotin , lymph node biopsy , abvd , chemotherapy , hodgkin's lymphoma , lesion , positron emission tomography , supraclavicular lymph nodes , hodgkin lymphoma , lymph , pathology , vincristine , surgery , cancer , metastasis , cyclophosphamide
Abstract Lung lesions of Hodgkin's lymphoma (HL) are rare and difficult to diagnose by nonsurgical biopsy. We herein present the case of a 72‐year‐old Japanese male who presented with accumulation of lung infiltrates and masses bilaterally on the lungs for 3 years. Although transbronchial lung biopsy (TBB) and computed tomography‐guided biopsy were conducted several times, his diagnosis remained inconclusive. On further deterioration of lung lesions, the patient was transferred to our hospital. Positron emission tomography revealed increased accumulation in the bilateral lungs and right supraclavicular lymph nodes. Surgical biopsy of the lymph node was performed. He was finally diagnosed with HL and underwent chemotherapy with doxorubicin, vinblastine, dacarbazine, and brentuximab vedotin. After chemotherapy, the lung lesion showed significant regression. A literature review indicated that the diagnostic success rate of TBB was low (18.5%) in cases of lung lesions in HL.