Open AccessEndobronchial brachytherapy combined with surgical procedure for synchronous multiple primary lung cancer: A case report
Author(s) -
Omori Kazuki,
Nomoto Yoshihito,
Kawamura Tomoko,
Kubooka Makiko,
Kawaguchi Koji,
Ii Noriko,
Takada Akinori,
Toyomasu Yutaka,
Sakuma Hajime
Publication year - 2021
Publication title -
thoracic cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.823
H-Index - 28
eISSN - 1759-7714
pISSN - 1759-7706
DOI - 10.1111/1759-7714.13911
Subject(s) - medicine , brachytherapy , lung cancer , lesion , radiation therapy , radiology , adverse effect , bronchitis , lung , surgery , oncology
The management of synchronous multiple primary lung cancer is a challenge. In this report, we describe our experience in a patient with three synchronous multiple cancers. The first lesion was completely surgically removed, the second lesion received postoperative irradiation, and the third lesion was treated with radiotherapy alone. Radiation therapies were performed using a combination of external irradiation and endobronchial brachytherapy. Endobronchial brachytherapy is an effective radiation therapy for endobronchial tumors owing to its advantage of high‐dose concentration. However, adverse events (AEs) such as hemoptysis or severe bronchitis are a problem. Thus, we have developed an applicator to keep the radioactive source in the center of the bronchial lumen. A total of 28 months after treatment, the patient had not experienced any relapses or AEs. Endobronchial brachytherapy using an applicator can be an alternative treatment for cases in which surgery is expected to lead to pulmonary dysfunction.