Open AccessDiagnostic value of microRNAs for malignant pleural mesothelioma: A mini‐review
Author(s) -
Han YanQiu,
Xu ShangCheng,
Zheng WenQi,
Hu ZhiDe
Publication year - 2021
Publication title -
thoracic cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.823
H-Index - 28
eISSN - 1759-7714
pISSN - 1759-7706
DOI - 10.1111/1759-7714.13746
Subject(s) - medicine , microrna , mesothelioma , diagnostic biomarker , oncology , cancer research , gene , cancer , pathology , bioinformatics , genetics , biology
Malignant pleural mesothelioma (MPM) is a type of cancer originating from the pleura with high aggressiveness and poor prognosis. A timely diagnosis is crucial to improve its prognosis. Laboratory biomarkers have significant advantages of reduced invasiveness, low cost, and are observer‐independent, and therefore represent a promising diagnostic tool for MPM. MicroRNA is a family of non‐coding RNA that regulates gene expression at the post‐transcriptional level. Accumulated studies showed that microRNA, either in tissue, circulating, and body fluid, has potential diagnostic value for various disorders. Here, we reviewed the diagnostic value of microRNA for MPM.