Open AccessFollow‐up of an occult tuberculosis scar cancer after resection of metastatic lesions
Author(s) -
Sun Mengyao,
Xu Yinghui,
Wang Xu,
Sun Chao,
Guo Ye,
Shao Guoguang,
Yang Zhiguang,
Liu Yunpeng,
Zhang Peng,
Qiu Shi,
Ma Kewei
Publication year - 2020
Publication title -
thoracic cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.823
H-Index - 28
eISSN - 1759-7714
pISSN - 1759-7706
DOI - 10.1111/1759-7714.13531
Subject(s) - medicine , adenocarcinoma , lung cancer , lung , radiology , tuberculosis , pneumonectomy , lymph node , occult , mediastinal lymph node , lesion , carcinoma , squamous carcinoma , pathology , cancer , metastasis , alternative medicine
A 61‐year‐old Chinese man with a history of tuberculosis was found to have a large mass in the left lower lobe and multiple ground‐glass nodules (GGNs) on lung computed tomography (CT). Post‐operative pathology showed lung squamous carcinoma in the left lower lobe and mediastinal lymph node metastases, which were confirmed as lung adenocarcinoma. Multiple gene sequencing was performed, and no relationship was observed between the two primary sites. Chemotherapy consisting of four cycles of gemcitabine plus cisplatin were prescribed for this patient after the operation. After a period of two‐year follow‐up, the lung adenocarcinoma was found to have progressed with new metastases in the right cervical lymph nodes which had the same pathology and gene mutation as the metastatic mediastinal lymph nodes removed two years previously. Meanwhile, a primary lesion was found following PET‐CT scan, and the tuberculosis scar was determined as its point of origin. In conclusion, we have found that a tuberculosis scar is a risk factor of lung cancer, especially adenocarcinoma, and more attention should be paid to close monitoring and follow‐up by clinicians.