Open AccessBrain cavernous hemangioma mimicking radiation‐induced necrosis in a patient with non‐small cell lung cancer
Author(s) -
Takamori Shinkichi,
Seto Takashi,
Jinnouchi Mikako,
Matsubara Taichi,
Haratake Naoki,
Miura Naoko,
Toyozawa Ryo,
Yamaguchi Masafumi,
Takenoyama Mitsuhiro
Publication year - 2020
Publication title -
thoracic cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.823
H-Index - 28
eISSN - 1759-7714
pISSN - 1759-7706
DOI - 10.1111/1759-7714.13494
Subject(s) - medicine , hemangioma , brain metastasis , magnetic resonance imaging , lung cancer , radiology , radiation therapy , pathological , anaplastic lymphoma kinase , pathology , metastasis , lung , cancer , malignant pleural effusion
In patients with non‐small cell lung cancer (NSCLC), stereotactic radiotherapy (SRT) is one of the standard therapies for those suffering with intracranial metastatic NSCLC. Radiation‐induced necrosis (RIN) sometimes occurs as the result of the delayed effects of SRT. The magnetic resonance imaging (MRI) of RIN typically shows hypointense and hyperintense lesions on T1‐ and T2‐weighted images, respectively. We herein report a patient with a growing brain cystic lesion mimicking RIN adjacent to a post‐radiation brain metastasis from NSCLC harboring anaplastic lymphoma kinase rearrangement. The patient underwent surgical resection of the brain tumor because of the symptoms. The pathological diagnosis was cavernous hemangioma, and the pathological findings were an encapsulated nodular mass composed of dilated, cavernous vascular spaces with no residual tumor or recurrence. Clinicians should be aware of the possibility for the development of a brain cavernous hemangioma following SRT in NSCLC patients.