English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Zendy Open

Presents the pdf analysis as premium feature

PDF Analysis

Insights

Presents the summarisation as premium feature

Summarisation

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the zaia usage as premium feature

ZAIA

Zendy Tools

Zendy Plus

Presents the access of premium content as premium feature

Premium Content

Background  Ground‐glass nodules ( GGNs ), which are possible precursors of lung cancer, attract increasing attention. Many studies have attempted to identify the characteristic imaging features of  GGNs  for their qualitative diagnosis; however, the comprehension of  GGNs  remains controversial. We performed this study to identify imaging characteristics helpful to the differential diagnosis of solitary  GGNs .    Methods  We retrospectively evaluated 112 solitary  GGNs  resected from 112 patients, pathologically examined after surgical resection. Imaging features of the  GGNs,  such as size, shape, a solid component, lobulation, spiculation, vascular convergence sign, pleural tag, and air cavity density, were assessed. Differences between malignant and benign nodules were analyzed using binary logistic regression analysis.    Results  Of the 112  GGNs , 82 were malignant and 30 were benign. A solid component, vascular convergence sign, and a larger diameter were risk factors for malignancy, with a sensitivity, specificity, and accuracy of 93.9%, 60.0%, and 84.8%, respectively. Lobulation, spiculation, air cavity densities, and pleural tags were also important indicators of malignancy, with positive predictive values of 93.5%, 83.3%, 91.7%, and 87.2%, respectively.    Conclusion   GGNs  with a solid component, vascular convergence sign, and a larger diameter are highly suggestive of malignancy. The possibility of a neoplasm should also be considered in the case of  GGNs  that show lobulation, spiculation, air cavity densities, or pleural tags. To obtain a comprehensive and accurate analysis of the nodules, three‐dimensional reconstruction is highly recommended.

Multi‐slice computed tomography characteristics of solitary pulmonary ground‐glass nodules: Differences between malignant and benign