Open AccessSpontaneous regression of non‐small cell lung cancer that progressed after multiple chemotherapies: A case report
Author(s) -
Chung Chaeuk,
Park Dong Il,
Kim Sun Young,
Kim Ju Ock,
Jung Sung Soo,
Park Hee Sun,
Moon Jae Young,
Kim Sung Min,
Cho Min Ji,
Jung Sang Ok,
Lee Choong Sik,
Lee Jeong Eun
Publication year - 2015
Publication title -
thoracic cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.823
H-Index - 28
eISSN - 1759-7714
pISSN - 1759-7706
DOI - 10.1111/1759-7714.12221
Subject(s) - medicine , lung cancer , oncology , regression , chemotherapy , statistics , mathematics
Spontaneous regression ( SR ) of cancer is defined as a complete or partial, temporary or permanent disappearance of all or at least some relevant parameters of malignant disease with inadequate or no treatment. SR of cancer is an extremely rare phenomenon. We report a case of a 67‐year‐old man who experienced SR of non‐small‐cell lung cancer ( NSCLC ), which progressed after fifth‐line chemotherapy and regressed after chemotherapy ceased. Surprisingly, the primary tumor size continued to decrease for more than 13 months and his general condition markedly improved after discontinuation of the chemotherapy. To our knowledge, this is the first report of SR in a patient with NSCLC that was not responsive to a fifth round of chemotherapy.