Open AccessTraffic‐related air pollution and lung cancer: A meta‐analysis
Author(s) -
Chen Gongbo,
Wan Xia,
Yang Gonghuan,
Zou Xiaog
Publication year - 2015
Publication title -
thoracic cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.823
H-Index - 28
eISSN - 1759-7714
pISSN - 1759-7706
DOI - 10.1111/1759-7714.12185
Subject(s) - medicine , lung cancer , meta analysis , odds ratio , confidence interval , air pollution , environmental health , nitrogen dioxide , checklist , air quality index , meteorology , chemistry , organic chemistry , psychology , physics , cognitive psychology
Background We conducted a meta‐analysis to evaluate the association between traffic‐related air pollution and lung cancer in order to provide evidence for control of traffic‐related air pollution. Methods Several databases were searched for relevant studies up to D ecember 2013. The quality of articles obtained was evaluated by the S trengthening the R eporting of O bservational S tudies in E pidemiology checklist. Statistical analysis, including pooling effective sizes and confidential intervals, was performed. Results A total of 1106 records were obtained through the database and 36 studies were included in our analysis. Among the studies included, 14 evaluated the association between ambient exposure to traffic‐related air pollution and lung cancer and 22 studies involved occupational exposure to air pollution among professional drivers. Twenty‐two studies were marked A level regarding quality, 13 were B level, and one was C level. Exposure to nitrogen dioxide (meta‐odds ratio [ OR] : 1.06, 95% confidence interval [ CI] : 0.99–1.13), nitrogen oxide (meta‐ OR : 1.04, 95% CI : 1.01–1.07), sulfur dioxide (meta‐ OR : 1.03, 95% CI : 1.02–1.05), and fine particulate matter (meta‐ OR : 1.11, 95% CI : 1.00–1.22) were positively associated with a risk of lung cancer. Occupational exposure to air pollution among professional drivers significantly increased the incidence (meta‐ OR : 1.27, 95% CI : 1.19–1.36) and mortality of lung cancer (meta‐ OR : 1.14, 95% CI : 1.04–1.26). Conclusion Exposure to traffic‐related air pollution significantly increased the risk of lung cancer.