Open AccessDemonstration program of population‐based lung cancer screening in C hina: Rationale and study design
Author(s) -
Zhou Qinghua,
Fan Yaguang,
Wu Ning,
Huang Yunchao,
Wang Ying,
Li Lu,
Liu Jiewei,
Wang Xinyun,
Li Weimin,
Qiao Youlin
Publication year - 2014
Publication title -
thoracic cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.823
H-Index - 28
eISSN - 1759-7714
pISSN - 1759-7706
DOI - 10.1111/1759-7714.12078
Subject(s) - medicine , lung cancer screening , lung cancer , context (archaeology) , population , cancer , chinese population , spiral computed tomography , intensive care medicine , oncology , surgery , environmental health , computed tomography , paleontology , biology , biochemistry , chemistry , gene , genotype
Background Lung cancer is the leading cause of cancer‐related death and has become an enormous economic burden in C hina. Low‐dose spiral computed tomography ( LDCT ) screening could reduce lung cancer mortality. The feasibility of conducting a population‐based lung cancer screening with LDCT in C hina is uncertain. Methods In 2010, a demonstration program of lung cancer screening was initiated in C hina. High‐risk individuals were enrolled in a cluster sampling design in different centers. Participants received baseline and annual screening with spiral CT and follow‐up information was collected. The objective of this program is to evaluate the feasibility of conducting population‐based LDCT lung cancer screening in the C hinese context. The rates of detection, early diagnosis and treatment are defined as indicators of program performance. The optimal management strategies for nodules are explored in the Chinese context based on experiences in other studies overseas. Results A demonstration program of ongoing prospective, multi‐center, population‐based lung cancer screening is being performed in China. Conclusions This demonstration program will provide opportunities to explore the feasibility of LDCT lung cancer screening in the C hinese setting.