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Assessment of the anti‐rheumatoid arthritis activity of Gastrodia elata (tian‐ma) and Radix aconitic lateralis preparata (fu‐zi) via network pharmacology and untargeted metabolomics analyses
Author(s) -
Yang Jie,
Zhang Yu,
Li WeiHong,
Guo BuFa,
Peng QiLun,
Yao WeiYi,
Gong DiHong,
Ding WeiJun
Publication year - 2021
Publication title -
international journal of rheumatic diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.795
H-Index - 41
eISSN - 1756-185X
pISSN - 1756-1841
DOI - 10.1111/1756-185x.14063
Subject(s) - gastrodia elata , metabolomics , isoflavonoid , traditional medicine , biochemistry , medicine , pharmacology , traditional chinese medicine , chemistry , chromatography , flavonoid , alternative medicine , pathology , antioxidant
Gastrodia elata and Radix aconiti lateralis preparrata are respectively named as Tian-Ma and Fu-Zi (TF) in Chinese. We explored the active components against rheumatoid arthritis (RA) from an extensively used couplet of Chinese herbs, Gastrodia elata and Radix aconiti lateralis preparata (TF) via untargeted metabolomics and network pharmacological approaches.