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Work disability in Argentinian patients with systemic lupus erythematosus is prevalent and it is due to ethnic, socioeconomic and disease‐related factors
Author(s) -
Pisoni Cecilia N.,
Muñoz Sebastián A.,
Tamborenea María N.,
García Mercedes,
Curti Ana,
Cappuccio Ana,
Rillo Oscar,
Imamura Patricia M,
Schneeberger Emilce,
Ballent Marcela,
Cousseau Mario L.,
Velasco Zamora Jorge,
Saurit Verónica,
Toloza Sergio,
Danielsen María C,
Bellomio Verónica I,
Graf Cesar,
Paira Sergio,
Cavallasca Javier,
Pons Estel Bernardo,
Moreno José L. C.,
Díaz Mónica,
Alba Paula,
Verando Marcela,
Tate Guillermo,
Mysler Eduardo,
Sarano Judith,
Civit Emma E.,
Risueño Fabián,
Álvarez Sepúlveda Pablo,
Larroude María S.,
Méndez Marcos F.,
Conforti Andrea,
Sohn Débora
Publication year - 2018
Publication title -
international journal of rheumatic diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.795
H-Index - 41
eISSN - 1756-185X
pISSN - 1756-1841
DOI - 10.1111/1756-185x.13269
Subject(s) - medicine , quality of life (healthcare) , socioeconomic status , ethnic group , logistic regression , systemic lupus erythematosus , rheumatology , observational study , multivariate analysis , disease , stepwise regression , cross sectional study , demography , physical therapy , gerontology , environmental health , population , pathology , nursing , sociology , anthropology
Objective To study the prevalence and the associated factors of work disability ( WD ) in systemic lupus erythematosus ( SLE ) patients. Methods A sample of 419 SLE patients from an observational cross‐sectional multicenter study was included. Sociodemographic features, disease characteristics, comorbidities, quality of life, unhealthy behaviors, and work‐related factors were measured in a standardized interview. Work disability was defined by patient self‐report of not being able to work because of SLE . To identify variables associated with work disability, two different multivariate regression models using a stepwise backward method were performed. Results Prevalence of WD due to SLE was 24.3%. Eighty‐nine percent were female and 51% were Caucasians. Mean disease duration was 8.9 ± 7.2 years, and median System Lupus International Collaborating Clinics/American College of Rheumatology damage index SLICC ‐ SDI was 1.5 (range 0–17). In stepwise multivariate logistic regression, living below the poverty line (odds ratio [ OR ] = 4.65), less than 12 years of education ( OR = 2.84), Mestizo ethnicity ( OR = 1.94) and SLICC ‐ SDI ( OR = 1.25) were predictors of WD . A second model was performed including patient‐derived measures; in this model sedentary lifestyle ( OR = 2.69) and lower emotional health domain score of the Lupus Quality of Life (LupusQoL) questionnaire ( OR = 1.03) were found to be associated to WD and a higher score in LupusQoL physical health domain ( OR = 0.93) was protective. Conclusion The prevalence of WD in Argentinian SLE patients was 24.3%. WD was associated with ethnic (Mestizo), socioeconomic (poverty) and disease‐related factors. Patient‐related outcomes such us sedentary lifestyle and poor emotional quality of life were also associated with WD .