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Sleep quality in women with systemic lupus erythematosus: contributing factors and effects on health‐related quality of life
Author(s) -
Mirbagher Leila,
Gholamrezaei Ali,
Hosseini Naeimeh,
Sayed Bonakdar Zahra
Publication year - 2016
Publication title -
international journal of rheumatic diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.795
H-Index - 41
eISSN - 1756-185X
pISSN - 1756-1841
DOI - 10.1111/1756-185x.12418
Subject(s) - medicine , quality of life (healthcare) , quality (philosophy) , sleep quality , psychiatry , cognition , nursing , philosophy , epistemology
Abstract Aim Sleep quality disturbances are common in patients with systemic lupus erythematosus ( SLE ). We evaluated sleep quality and its contributors in women with SLE . Also we evaluated the effects of sleep quality disturbance on patients' health‐related quality of life ( HRQ o L ). Methods Sleep quality was assessed in 77 women with SLE (age 36.5 ± 10.1 years) using the P ittsburgh S leep Q uality I ndex ( PSQI ). Disease activity and cumulative disease damage were assessed with standard indices. Patients completed the H ospital A nxiety and D epression S cale and L upus Q o L . Univariate and multivariate analyses were performed to find contributors of poor sleep quality and association of sleep quality with HRQ o L . Results Poor sleep quality was present in 44 patients (57.1%). Poor sleepers were older ( P = 0.015) and had higher body mass index ( P = 0.027) and more severe anxiety ( P < 0.001) and depression symptoms ( P < 0.007) compared with good sleepers. In the logistic regression model, age (β = 1.16, P = 0.006), disease activity (β = 1.10, P = 0.050), and anxiety/depression composite score (β = 1.16, P = 0.008) were independent contributors of poor sleep quality. Poor sleepers had impaired HRQ o L in almost all domains of the L upus Q o L than good sleepers ( P < 0.05). Conclusion Poor sleep quality is common in women with SLE and significantly impairs their HRQ o L . Age, disease activity and psychological factors were determinants of sleep quality in our study. Studies with objective sleep measures as well as interventional studies are warranted in this regard.