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Functional gastrointestinal disorders in patients with familial M editerranean fever
Author(s) -
Börekci Elif,
Celikbilek Mehmet,
Soytürk Müjde,
Akar Servet,
Börekci Hasan,
Günaydin Ilhan
Publication year - 2017
Publication title -
international journal of rheumatic diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.795
H-Index - 41
eISSN - 1756-185X
pISSN - 1756-1841
DOI - 10.1111/1756-185x.12207
Subject(s) - medicine , familial mediterranean fever , irritable bowel syndrome , constipation , gastroenterology , functional gastrointestinal disorder , functional constipation , gastrointestinal disease , diarrhea , case control study , disease
Aim Familial Mediterranean fever ( FMF ) is an autosomal recessive autoinflammatory disease characterised by recurrent episodes of fever and polyserositis. To date, insufficient data regarding the prevalence of functional gastrointestinal disorders such as irritable bowel syndrome ( IBS ) and functional dyspepsia ( FD ) have been reported in patients with FMF . This study aimed to determine the prevalence of functional gastrointestinal disorders in patients with FMF . Methods This study included 122 patients with FMF and a control group of 122 healthy volunteers who were similar with respect to age and sex. Clinical data were collected and gastrointestinal complaints were evaluated according to the Rome III criteria. Results IBS was found in 18% of the patients and 10.7% of the controls ( P > 0.05). Dyspepsia was reported in 37.7% of the patients and 35.2% of the controls. Constipation was significantly higher in the control group (15.6% vs . 7.4%, P = 0.045), whereas diarrhoea was reported significantly more often in patients with FMF ( P = 0.001). Conclusions IBS and dyspepsia were not increased in patients with FMF , whereas diarrhoea was more frequently reported.