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Gallium‐68 PSMA uptake in adrenal adenoma
Author(s) -
Law W Phillip,
Fiumara Frank,
Fong William,
Miles Kenneth A
Publication year - 2016
Publication title -
journal of medical imaging and radiation oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.31
H-Index - 43
eISSN - 1754-9485
pISSN - 1754-9477
DOI - 10.1111/1754-9485.12357
Subject(s) - medicine , adenoma , gallium , adrenal adenoma , chemistry , organic chemistry
Summary Gallium‐68 ( G a‐68) labelled prostate‐specific membrane antigen ( PSMA ) imaging by positron emission tomography ( PET ) has emerged as a promising tool for staging of prostate cancer and restaging of disease in recurrence or biochemical failure after definitive treatment of prostate cancer. Ga‐68 PSMA PET produces high target‐to‐background images of prostate cancer and its metastases which are reflective of the significant overexpression of PSMA in these cells and greatly facilitates tumour detection. However, relatively little is known about the PSMA expression of benign neoplasms and non‐prostate epithelial malignancies. This is a case report of PSMA uptake in an adrenal adenoma incidentally discovered on PET performed for restaging of biochemically suspected prostate cancer recurrence. With the increasing use of PSMA PET in the management of prostate cancer – and the not infrequent occurrence of adrenal adenomas – the appearance of low‐ to moderate‐grade PSMA uptake in adrenal adenomas should be one with which reporting clinicians are familiar.