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Application value of MRI combined with positron emission tomography ( PET )/ CT in diagnosis and preoperative staging of tongue squamous cell carcinoma
Author(s) -
Chen Wenbo,
Zhang Chunxing,
Zhang Shuixing,
Liang Long,
Zhang Bin,
Liu Chunling,
Zhang Zhonglin,
Liang Changhong
Publication year - 2015
Publication title -
journal of medical imaging and radiation oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.31
H-Index - 43
eISSN - 1754-9485
pISSN - 1754-9477
DOI - 10.1111/1754-9485.12282
Subject(s) - medicine , positron emission tomography , stage (stratigraphy) , nuclear medicine , radiology , tongue , pathological staging , pathological , t stage , basal cell , standardized uptake value , cancer staging , significant difference , cancer , pathology , paleontology , biology
This study aimed to compare and analyse the findings of tongue squamous cell carcinoma ( TSCC ) on MRI and positron emission tomography ( PET )/ CT and explore the diagnostic utility of combined MRI‐PET / CT in the diagnosis and preoperative staging of TSCC . Methods A prospective analysis of MRI and PET / CT data in 18 TSCC cases was performed. Cases were comprehensively staged on MRI and PET / CT preoperatively according to A merican J oint C ommittee on C ancer ( AJCC ) staging criteria and confirmed by pathological results. Results The highest and lowest sensitivities of preoperative AJCC staging I – IV using MRI alone, PET / CT alone and combined MRI‐PET / CT were 100.0%, 100.0% and 100.0% (stage II ) and 50.4%, 55.6% and 55.6% (stage I ), respectively. The highest specificities were 100.0%, 100.0% and 100.0% (stage II ), and the highest correct rates were 100.0%, 96.5% and 100.0% (stage II ). Compared with the postoperative pathological staging, preoperative staging showed no significant difference for stages I – II and IV ( P > 0.05); however, stage III showed a significant difference ( P < 0.05). When combined MRI‐PET / CT was compared with MRI alone in the accuracy of preoperative TSCC staging, there was no significant difference for stages I – III ( P > 0.05), but there was a significant difference for stage IV ( P < 0.05). Conclusions Combined MRI and PET / CT could serve as an important tool for the accurate diagnosis and preoperative staging of TSCC and could improve the accuracy of preoperative TSCC staging.