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A comparison between three‐dimensional conformal radiotherapy combined with interventional treatment and interventional treatment alone for hepatocellular carcinoma with portal vein tumour thrombosis
Author(s) -
Lu DongHui,
Fei ZhenLe,
Zhou JunPing,
Hu ZongTao,
Hao WenSheng
Publication year - 2015
Publication title -
journal of medical imaging and radiation oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.31
H-Index - 43
eISSN - 1754-9485
pISSN - 1754-9477
DOI - 10.1111/1754-9485.12207
Subject(s) - medicine , hepatocellular carcinoma , portal vein , radiation therapy , portal vein thrombosis , radiology , thrombosis , carcinoma , gastroenterology
We investigated the therapeutic effects of three‐dimensional conformal radiotherapy combined with transcatheter arterial chemoembolisation ( TACE ) for hepatocellular carcinoma ( HCC ) with portal vein tumour thrombosis ( PVTT ). Methods Sixty‐three HCC patients with PVTT were divided into two groups. Group A (30 patients) was treated with three‐dimensional conformal radiotherapy followed by 2–3 series of TACE , while group B (33 patients) was only treated with TACE . Results The 1‐ and 2‐year survival rates of group A were 62.40% and 20.81%, respectively, with a mean survival time of 13.0 months. The 1‐ and 2‐year survival rates of group B were 56.49% and 18.83%, respectively, with a mean survival time of 9.0 months. There were significant differences between the two groups (log‐rank chi‐square value = 3.950, P = 0.047). Conclusion Three‐dimensional conformal radiotherapy combined with TACE can significantly improve clinical outcomes in patients with HCC and PVTT compared with TACE alone.