Open AccessExpression of inflammasome complex mRNA and its targeted microRNA in type 2 diabetes mellitus: A possible predictor of the severity of diabetic nephropathy
Author(s) -
Bhattacharjee Chandra K.,
Paine Suman K.,
Mahanta Jagadish,
Borphukan Sawjib,
Borah Prasanta K.
Publication year - 2019
Publication title -
journal of diabetes
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.949
H-Index - 43
eISSN - 1753-0407
pISSN - 1753-0393
DOI - 10.1111/1753-0407.12845
Subject(s) - inflammasome , medicine , diabetic nephropathy , diabetes mellitus , concomitant , microrna , type 2 diabetes mellitus , nephropathy , caspase 1 , bioinformatics , endocrinology , receptor , gene , genetics , biology
Highlights Concomitant elevated expression of Caspase‐1 in respect of reduced eGFR among DN may serve as better explainable marker for the adverse prognosis of the disease Study may open new horizon to understand patho‐mechanism with the aid of Inflammasome‐complex.