Open AccessResistance training reduces metabolic syndrome and inflammatory markers in older women: A randomized controlled trial
Author(s) -
Tomeleri Crisieli M.,
Souza Mariana F.,
Burini Roberto C.,
Cavaglieri Cláudia R.,
Ribeiro Alex S.,
Antunes Melissa,
Nunes João P.,
Venturini Danielle,
Barbosa Décio S.,
Sardinha Luís B.,
Cyrino Edilson S.
Publication year - 2018
Publication title -
journal of diabetes
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.949
H-Index - 43
eISSN - 1753-0407
pISSN - 1753-0393
DOI - 10.1111/1753-0407.12614
Subject(s) - medicine , metabolic syndrome , waist , randomized controlled trial , body mass index , insulin resistance , blood pressure , physical therapy , endocrinology , obesity
Background This study analyzed the effects of a 12‐week resistance training (RT) program without dietary interventions on metabolic syndrome (MetS) components and inflammatory biomarkers in older women. Methods Fifty‐three older women (mean [±SD] age 70.4 ± 5.7 years; mean body mass index 26.7 ± 4.0 kg/m 2 ) were randomly assigned to a training group (TG; n = 26) that performed 12 weeks of an RT program or a control group (CG; n = 27) that did not perform any type of physical exercise over the same period. Body composition (dual energy X‐ray absorptiometry), muscular strength (one‐repetition maximum tests), blood pressure (BP), and blood sample measurements were performed before and after intervention. Results After the 12‐week period, there were significantly reductions ( P < 0.05) in glucose levels (−20.4% vs −0.3%), waist circumference (−1.5% vs +2.0%), and systolic BP (−6.2% vs +0.9%), and complete normalization of MetS prevalence (18% at baseline vs. 0% after 12‐weeks RT) in the TG. Moreover, C‐reactive protein and tumor necrosis factor‐α concentrations decreased in the TG (−28.6% and −21.6%, respectively), but increased in the CG (+34.5% and +13.3%, respectively). In addition there were positive improvements in the MetS Z ‐score in the TG but not CG (−21.6% vs +13.3%, respectively). Conclusion The results suggest that a 12‐week RT program seems to effectively reduce MetS components and inflammatory biomarkers in older women, regardless of dietary intervention. The RT‐induced adaptations in body composition and inflammatory biomarkers appear to be related to healthy adaptations in risk factors for MetS.