Open AccessShort sleep duration and longer daytime napping are associated with non‐alcoholic fatty liver disease in Chinese adults
Author(s) -
Peng Kui,
Lin Lin,
Wang Zhengyi,
Ding Lin,
Huang Ya,
Wang Po,
Xu Yu,
Lu Jieli,
Xu Min,
Bi Yufang,
Wang Weiqing,
Chen Yuhong,
Ning Guang
Publication year - 2017
Publication title -
journal of diabetes
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.949
H-Index - 43
eISSN - 1753-0407
pISSN - 1753-0393
DOI - 10.1111/1753-0407.12489
Subject(s) - medicine , nap , odds ratio , fatty liver , obesity , population , metabolic syndrome , diabetes mellitus , cross sectional study , confidence interval , disease , endocrinology , pathology , environmental health , psychology , neuroscience
Background Epidemiologic studies have reported conflicting results on the relationship between short sleep duration and non‐alcoholic fatty liver disease ( NAFLD ). There are no previous studies investigating the effect of daytime napping on NAFLD . In the present study we examined the associations between NAFLD and both nightly sleep duration and daytime napping in a middle‐aged and elderly Chinese population. Methods This cross‐sectional community‐based population study was performed on 8559 individuals aged ≥40 years. Sleep duration and the duration of daytime napping were self‐reported using a standardized questionnaire; NAFLD was diagnosed by ultrasonography. Results In this study sample, the overall prevalence of NAFLD was 30.4%. There was an inverse association between sleep duration and the risk of prevalent NAFLD . In multivariate analysis, the odds ratios ( ORs ) and 95% confidence intervals ( CIs ) of prevalent NAFLD for decreasing sleep duration categories (≥9, 8.1–9, 7.1–8, 6.1–7, and ≤6.1 h) were 1.00 (reference), 1.38 (1.13–1.70), 1.32 (1.08–1.61), 1.29 (1.04–1.60), and 1.66 (1.28–2.15), respectively ( P trend = 0.0073). Compared with participants without a daytime napping habit, nap takers with a longer nap duration (>0.5 h) had an increased risk of prevalent NAFLD ( OR 1.22; 95% CI 1.06–1.41). The associations of sleep duration and daytime napping duration with NAFLD were generally consistent across different categories of age and obesity, metabolic syndrome, and insulin resistance status. Conclusions Short sleep duration and longer daytime napping were associated with an increased risk of prevalent NAFLD in a middle‐aged and elderly Chinese population.