Open AccessPrevalence of diabetes mellitus and prediabetes in the adult R omanian population: PREDATORR study
Author(s) -
Mota Maria,
Popa Simona Georgiana,
Mota Eugen,
Mitrea Adina,
Catrinoiu Doina,
Cheta Dan Mircea,
Guja Cristian,
Hancu Nicolae,
IonescuTirgoviste Constantin,
Lichiardopol Radu,
Mihai Bogdan Mircea,
Popa Amorin Remus,
Zetu Cornelia,
Bala Cornelia Gabriela,
Roman Gabriela,
Serafinceanu Cristian,
Serban Viorel,
Timar Romulus,
Veresiu Ioan Andrei,
Vlad Adrian Radu
Publication year - 2016
Publication title -
journal of diabetes
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.949
H-Index - 43
eISSN - 1753-0407
pISSN - 1753-0393
DOI - 10.1111/1753-0407.12297
Subject(s) - prediabetes , medicine , diabetes mellitus , dyslipidemia , overweight , population , impaired glucose tolerance , abdominal obesity , impaired fasting glucose , obesity , epidemiology , cross sectional study , demography , gerontology , metabolic syndrome , type 2 diabetes , endocrinology , environmental health , pathology , sociology
Background The PREDATORR ( PRE valence of D i A be T es mellitus, prediabetes, overweight, O besity, dyslipidemia, hyperuricemia and chronic kidney disease in R omania) study is the first national study analyzing the prevalence of diabetes mellitus ( DM ) and prediabetes, and their association with cardiometabolic, sociodemographic, and lifestyle risk factors in the R omanian population aged 20–79 years. Methods This was an epidemiological study with a stratified, cross‐sectional, cluster random sampling design. Sociodemographic, lifestyle, and anamnestic data were collected through self‐ and interviewer‐administered questionnaires, and biochemical assays and oral glucose tolerance tests were performed. Results In all, 2728 participants from 101 clinics of general practitioners were randomly selected, with a probability proportional to population size according to the 2002 R omanian C ensus. The participation rate was 99.6%. Impaired glucose regulation (prediabetes, known and unknown DM ) was found in 28.1% of the study population. The overall age‐ and sex‐adjusted prevalence of DM was 11.6% (95% CI 9.6%–13.6%), of which 2.4% (95% CI 1.7%–3.1%) had unknown DM . The prevalence of DM increased with age and was higher in men than in women. The age‐ and sex‐adjusted prevalence of prediabetes was 16.5% (95% CI 14.8%–18.2%), with the highest percentage in the 60–79 year age group and in women. Obesity, abdominal obesity, dyslipidemia, low education level, and a family history of diabetes were associated with glucose metabolism disorders. Conclusions The PREDATORR study shows a high prevalence of impaired glucose regulation in the adult R omanian population, providing data on the prevalence of DM and prediabetes and their association with several risk factors.