Open AccessIncidence of type 2 diabetes and number of events attributable to abdominal obesity in C hina: A cohort study
Author(s) -
Xue Haifeng,
Wang Chao,
Li Ying,
Chen Jichun,
Yu Ling,
Liu Xiaoqing,
Li Jianxin,
Cao Jie,
Deng Ying,
Guo Dongshuang,
Yang Xueli,
Huang Jianfeng,
Gu Dongfeng
Publication year - 2016
Publication title -
journal of diabetes
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.949
H-Index - 43
eISSN - 1753-0407
pISSN - 1753-0393
DOI - 10.1111/1753-0407.12273
Subject(s) - medicine , abdominal obesity , type 2 diabetes , diabetes mellitus , incidence (geometry) , obesity , waist , population , risk factor , cohort , attributable risk , cohort study , epidemiology , endocrinology , environmental health , physics , optics
Background The aim of the present study was to estimate the incidence of type 2 diabetes (T2D) and the number of diabetes events attributable to abdominal obesity in C hina. Methods A cohort study was conducted in a sample of 24 996 Chinese adults aged 35–74 years, with 19.9% of subjects lost to follow‐up. Waist circumference ( WC ) was measured at baseline in 1998 and 2000–01, and abdominal obesity was defined as WC ≥ 90 cm in men and ≥80 cm in women. Information on incident diabetes was collected during follow‐up in 2007–08. We estimated the number of T2D events attributed to abdominal obesity using confounder‐adjusted population‐attributable risk, incidence of diabetes, and the population size of C hina in 2010. Results After a mean follow‐up of 8.0 years, the age‐standardized incidence of T2D was 9.6 and 9.2 per 1000 person‐years in men and women, respectively. Abdominal obesity accounted for 28.1% (95% confidence interval [ CI ] 14.8%, 40.5%) of incident diabetes among men and 41.2% (95% CI 28.3%, 52.6%) among women using the diagnostic criteria of abdominal obesity recommended by the International Diabetes Federation. We estimated that, in 2010, 2.4 (95% CI 1.5, 3.2) million diabetes events were attributable to abdominal obesity: 1.0 (95% CI 0.5, 1.4) million in men and 1.4 (95% CI 1.0, 1.8) million in women. Conclusions Abdominal obesity is a major risk factor for T2D. Strengthening programs and initiatives for preventing and controlling obesity focusing on lifestyle changes should be a priority in the national strategy to reduce diabetes burden in C hina.