Open AccessImpact of night sleep duration on glycemic and triglyceride levels in C hinese with different glycemic status 不同血糖水平的中国人群的夜晚睡眠时间对血糖和甘油三酯水平的影响
Author(s) -
Zheng Yu,
Wang Anping,
Pan Changyu,
Lu Juming,
Dou Jingtao,
Lu Zhaohui,
Ba Jianming,
Wang Baoan,
Mu Yiming
Publication year - 2015
Publication title -
journal of diabetes
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.949
H-Index - 43
eISSN - 1753-0407
pISSN - 1753-0393
DOI - 10.1111/1753-0407.12186
Subject(s) - medicine , glycemic , diabetes mellitus , confounding , body mass index , sleep (system call) , triglyceride , endocrinology , glycemic load , glycemic index , cholesterol , computer science , operating system
Background The aim of the present study was to assess the relationship between night sleep duration and glycemic and triglyceride ( TG ) levels among people with different glycemic status. Methods In all, 18 121 subjects aged ≥40 years were enrolled in this cross‐sectional study, including 4318 with impaired glucose regulation ( IGR ), 4225 with diabetes, and 9578 with normal glucose regulation ( NGR ). The IGR + diabetes and NGR groups were divided into three subgroups according to self‐reported night sleep duration as follows: (i) <6 h; (ii) 6–9 h; and (iii) >9 h. The associations of sleep duration with HbA1c , fasting plasma glucose ( FPG ), 2‐h post‐load plasma glucose ( PPG ), and TG levels were examined. Results Long night sleep duration (>9 h) was associated with higher HbA1c , FPG , PPG , and TG levels compared with sleep duration of 6–9 h ( P < 0.01 for all) in the IGR + diabetes group, but not in the NGR group. This association was adjusted for potential confounders, including body mass index and depressive symptoms, and remained significant even after adjusting for snoring. A significant interaction between sleep duration and TG or snoring was observed for HbA1c levels, which attenuated the sleep– HbA1c association in the IGR + diabetes group. However, no significant association was observed between short night sleep duration and HbA1c levels. Conclusions Long night sleep duration is associated with higher HbA1c , FPG , PPG , and TG levels in IGR and diabetes patients, independent of potential confounders. This may be important in clinical management of IGR and diabetes patients.