Open AccessMeta‐analysis of prospective studies on the effects of nut consumption on hypertension and type 2 diabetes mellitus 对食用坚果对高血压和2型糖尿病的影响的前瞻性研究进行的meta分析
Author(s) -
Guo Kai,
Zhou Zhiwen,
Jiang Yibo,
Li Wei,
Li Yigang
Publication year - 2015
Publication title -
journal of diabetes
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.949
H-Index - 43
eISSN - 1753-0407
pISSN - 1753-0393
DOI - 10.1111/1753-0407.12173
Subject(s) - medicine , meta analysis , confidence interval , type 2 diabetes mellitus , prospective cohort study , relative risk , diabetes mellitus , nut , type 2 diabetes , random effects model , cohort study , endocrinology , structural engineering , engineering
Background Inconclusive reports have been published on the consumption of nuts and the risk of hypertension and type 2 diabetes mellitus ( T2DM ). We performed a meta‐analysis of prospective studies to assess the effects of nut consumption on hypertension and T2DM risks. Methods A PUBMED and EMBASE database search was performed. Summary relative risks ( SRRs ) and 95% confidence intervals ( CIs ) were calculated using a random‐effects model. Q and I 2 statistics were used to examine between‐study heterogeneity. Results A total of eight articles with nine prospective cohort studies (three hypertension studies and six T2DM studies) were selected. Using random effects models, we found that compared with never/rare consumers of nuts, those consuming >2 servings per week had an 8% lower risk of hypertension ( SRR = 0.92, 95% CI : 0.87–0.97, P heterogeneity = 0. 590, I 2 = 0%), while consumption of nuts at one serving per week had similar risk ( SRR = 0.97, 95% CI : 0.83–1.13). In addition, nuts consumption was not associated with risk of T2DM ( SRRs = 0. 98, 95% CI : 0.84–1.15; P heterogeneity = 0. 008, I 2 = 67.7%) on the basis of the highest versus lowest analysis. This null association was also shown in the dose‐response analysis. Conclusion Findings from this meta‐analysis indicate that consumption of nuts (>2 servings/week) may be inversely associated with hypertension risk, but not with T2DM risk.