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Minicell‐based fungal RNAi delivery for sustainable crop protection
Author(s) -
Islam Md Tabibul,
Davis Zachery,
Chen Lisa,
Englaender Jacob,
Zomorodi Sepehr,
Frank Joseph,
Bartlett Kira,
Somers Elisabeth,
Carballo Sergio M.,
Kester Mark,
Shakeel Ameer,
Pourtaheri Payam,
Sherif Sherif M.
Publication year - 2021
Publication title -
microbial biotechnology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.287
H-Index - 74
ISSN - 1751-7915
DOI - 10.1111/1751-7915.13699
Subject(s) - biology , rna silencing , rna interference , gene silencing , chitin synthase , dicer , gene , microbiology and biotechnology , rna , genetics , chitin , biochemistry , chitosan
Spray‐induced gene silencing (SIGS) using topical dsRNA applications has risen as a promising, target‐specific, and environmentally‐friendly disease management strategy against phytopathogenic fungi. We demonstrated that minicell‐encapsulated dsRNA (ME‐dsRNA) halted gray mold disease progression in strawberries. ME‐dsRNAs offer a platform that can readily be translated to large‐scale production and deployed in open‐field applications to control gray mold in strawberries.

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