Open AccessRevealing formate production from carbon monoxide in wild type and mutants of Rnf‐ and Ech‐containing acetogens, Acetobacterium woodii and Thermoanaerobacter kivui
Author(s) -
Schwarz Fabian M.,
Ciurus Sarah,
Jain Surbhi,
Baum Christoph,
Wiechmann Anja,
Basen Mirko,
Müller Volker
Publication year - 2020
Publication title -
microbial biotechnology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.287
H-Index - 74
ISSN - 1751-7915
DOI - 10.1111/1751-7915.13663
Subject(s) - formate , biochemistry , bioenergetics , chemistry , bacteria , biology , catalysis , genetics , mitochondrion
In this study we focused on the two acetogenic bacteria Acetobacterium woodii and Thermoanaerobacter kivui and demonstrated their potential as whole cell biocatalysts for the conversion of CO into the bulk chemicals acetate and formate. Notably, no external electron donor such as H 2 was required for the conversion of CO. We could further shed light into the dark of CO utilization in A. woodii and T. kivui by using mutants with deficiencies in key enzyme activities of the central metabolism.