Sulfane sulfur‐activated actinorhodin production and sporulation is maintained by a natural gene circuit in  Streptomyces coelicolor | Zendy

Lu Ting | Zendy; Cao Qun | Zendy; Pang Xiuhua | Zendy; Xia Yongzhen | Zendy; Xun Luying | Zendy; Liu Huaiwei | Zendy

Open Access

Sulfane sulfur‐activated actinorhodin production and sporulation is maintained by a natural gene circuit in Streptomyces coelicolor

Author(s) -

Lu Ting,

Cao Qun,

Pang Xiuhua,

Xia Yongzhen,

Xun Luying,

Liu Huaiwei

Publication year - 2020

Publication title -

microbial biotechnology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.287

H-Index - 74

ISSN - 1751-7915

DOI - 10.1111/1751-7915.13637

Subject(s) - actinorhodin , streptomyces coelicolor , biology , aspergillus nidulans , promoter , sulfur , benzothiophene , biochemistry , gene , streptomyces , transcription (linguistics) , transcription factor , gene cluster , bacteria , genetics , chemistry , gene expression , mutant , linguistics , philosophy , organic chemistry , thiophene

Sulfane sulfur activates actinorhodin production and sporulation in Streptomyces coelicolor . A gene cluster controlling intracellular sulfane sulfur levels is identified. Genetically modifying this gene cluster can change sulfane sulfur levels, thereby altering the actinorhodin production and sporulation.

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