Open AccessSulfane sulfur‐activated actinorhodin production and sporulation is maintained by a natural gene circuit in Streptomyces coelicolor
Author(s) -
Lu Ting,
Cao Qun,
Pang Xiuhua,
Xia Yongzhen,
Xun Luying,
Liu Huaiwei
Publication year - 2020
Publication title -
microbial biotechnology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.287
H-Index - 74
ISSN - 1751-7915
DOI - 10.1111/1751-7915.13637
Subject(s) - actinorhodin , streptomyces coelicolor , biology , aspergillus nidulans , promoter , sulfur , benzothiophene , biochemistry , gene , transcription (linguistics) , gene cluster , streptomyces , transcription factor , bacteria , chemistry , genetics , gene expression , mutant , linguistics , philosophy , organic chemistry , thiophene
Sulfane sulfur activates actinorhodin production and sporulation in Streptomyces coelicolor . A gene cluster controlling intracellular sulfane sulfur levels is identified. Genetically modifying this gene cluster can change sulfane sulfur levels, thereby altering the actinorhodin production and sporulation.