Open AccessProtective effect of Lactobacillus salivarius Li01 on thioacetamide‐induced acute liver injury and hyperammonaemia
Author(s) -
Yang Liya,
Bian Xiaoyuan,
Wu Wenrui,
Lv Longxian,
Li Yating,
Ye Jianzhong,
Jiang Xianwan,
Wang Qing,
Shi Ding,
Fang Daiqiong,
Wu Jingjing,
Wang Kaicen,
Wang Qiangqiang,
Xia Jiafeng,
Xie Jiaojiao,
Lu Yanmeng,
Li Lanjuan
Publication year - 2020
Publication title -
microbial biotechnology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.287
H-Index - 74
ISSN - 1751-7915
DOI - 10.1111/1751-7915.13629
Subject(s) - lactobacillus salivarius , thioacetamide , liver injury , immunology , medicine , endocrinology , pharmacology , biology , lactobacillus , biochemistry , fermentation
Lactobacillus salivarius Li01 improved TAA‐induced acute liver injury and hyperammonemia which was mediated by restoring destroyed gut microbiota and barrier function, improving TAA‐induced liver damage and systemic inflammation, and alleviating hyperammonaemia, neuro‐inflammation and damaged cognitive function.