Open AccessGenome Update. Let the consumer beware: Streptomyces genome sequence quality
Author(s) -
Studholme David J.
Publication year - 2016
Publication title -
microbial biotechnology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.287
H-Index - 74
ISSN - 1751-7915
DOI - 10.1111/1751-7915.12344
Subject(s) - genbank , genome , whole genome sequencing , sequence assembly , quality (philosophy) , sequence (biology) , streptomyces , computational biology , biology , genetics , microbiology and biotechnology , gene , bacteria , philosophy , gene expression , transcriptome , epistemology
Summary A genome sequence assembly represents a model of a genome. This article explores some tools and methods for assessing the quality of an assembly, using publicly available data for Streptomyces species as the example. There is great variability in quality of assemblies deposited in GenBank. Only in a small minority of these assemblies are the raw data available, enabling full appraisal of the assembly quality.