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Novel biomarkers for the diagnosis and prognosis of gallbladder cancer
Author(s) -
Lin Hong Ze,
Zhang Tao,
Chen Ming Yu,
Shen Ji Liang
Publication year - 2021
Publication title -
journal of digestive diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.684
H-Index - 51
eISSN - 1751-2980
pISSN - 1751-2972
DOI - 10.1111/1751-2980.12966
Subject(s) - medicine , gallbladder cancer , malignancy , biliary tract cancer , disease , gallbladder , cancer , biomarker , clinical significance , oncology , intensive care medicine , biochemistry , chemistry , gemcitabine
Gallbladder cancer (GBC) is the most common form of biliary tract malignancy with a dismal prognosis. A poor outcome in patients with GBC is related to the aggressive nature of the tumor, delayed diagnosis, and a lack of reliable biomarkers and effective treatment. Therefore, early diagnosis and accurate disease assessment are crucial to prolonging the patient survival. Identification of novel prognostic and diagnostic biomarkers may help improve the early diagnostic rate and develop specific targeted treatments for patients with GBC. We herein review the novel biomarkers that may be associated with the diagnosis and prognosis in GBC and their potential clinical significance in the management of GBC.