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Development of a validated Chinese version of the inflammatory bowel disease disability index
Author(s) -
Zhang Jing Jing,
Lou Dan Na,
Ma Han,
Yu Chao Hui,
Chen Li Hua,
Li You Ming
Publication year - 2020
Publication title -
journal of digestive diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.684
H-Index - 51
eISSN - 1751-2980
pISSN - 1751-2972
DOI - 10.1111/1751-2980.12836
Subject(s) - medicine , inflammatory bowel disease , hamd , cronbach's alpha , intraclass correlation , quality of life (healthcare) , rating scale , physical therapy , depression (economics) , disease , gastroenterology , psychometrics , clinical psychology , psychology , significant difference , developmental psychology , nursing , economics , macroeconomics
Objective The inflammatory bowel disease disability index (IBD‐DI) has been used to evaluate functional status for patients with inflammatory bowel diseases (IBD). The study aimed to develop a reliable Chinese version of IBD‐DI (C‐IBD‐DI). Methods Consecutive patients with IBD and healthy controls were recruited from June 2016 to July 2017 in the First Affiliated Hospital, College of Medicine, Zhejiang University (Hangzhou, Zhejiang Province, China) to complete an inflammatory bowel disease questionnaire‐32 (IBDQ‐32), Hamilton's anxiety rating scale (HAMA) and Hamilton's depression rating scale‐24 items (HAMD‐24). The validation process included item reduction, reliability and validity tests. Results Altogether 122 patients with IBD completed the validation process. Factor analysis reduced the C‐IBD‐DI to 13 items. Cronbach's α coefficient was 0.90. The C‐IBD‐DI scores were correlated with IBDQ‐32 score ( r = −0.79, P < 0.001), HAMA ( r = 0.78, P < 0.001) and HAMD‐24 ( r = 0.81, P < 0.001). The total score of C‐IBD‐DI was significantly higher in patients with active IBD than in those in remission. The intraclass correlation coefficient was 0.83 in the stable IBD group, representing a good test–retest reliability. Those with improved disease activity had a significantly lower C‐IBD‐DI score at the follow‐up visit than at baseline. Patients with IBD had worse disability levels and quality of life than the controls, and were more likely to be anxious and depressed, especially those with active IBD. Conclusions The validated C‐IBD‐DI comprising 13 questions has highly acceptable reliability and validity. Multicenter studies including large sample sizes are needed to further confirm our results.